HAO1 Protein (AA 1-370) (His tag)

Produktnummer ABIN667522

Produktdetails

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-370

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HAO1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: HAO1, 1-370aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.5M NaCl

Lagerung: 4 °C

Antigendetails

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Andere Bezeichnung: HAO1 (HAO1 Produkte)

Synonyme: hao1 Protein, GOX Protein, GOX1 Protein, HAOX1 Protein, Gox1 Protein, XDH1 Protein, Hao-1 Protein, hydroxyacid oxidase 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog Protein, hydroxyacid oxidase 1, liver Protein, CpipJ_CPIJ013711 Protein, THEYE_A0075 Protein, hao1 Protein, HAO1 Protein, hao1.L Protein, Hao1 Protein

Hintergrund: HAO1, also known as glycolate oxidase, is a member of the superfamily of the alpha hydroxy acid oxidases(HAO) enzymes. It catalyzes the FMN mediated oxidation of glycolate to glyoxylate and glyoxylate to oxalate with reduction of oxygen to hydrogen peroxide. It is most highly expressed in liver and pancreas and is most active on twocarbon substrates such as glycolate. Recently, it has been identified as a major contributor to hyperoxaluria, a disorder in which large deposits of calcium oxalate form kidney stones. Recombinant human HAO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacid oxidase 1, GOX (glycolate oxidase), GOX1, HAOX1. NCBI no.: NP_060015

Molekulargewicht: 45.0 kDa(406aa), confirmed by MALDI-TOF

Pathways: Monocarboxylic Acid Catabolic Process