DCUN1D2 Protein (AA 1-259) (His tag)

Produktnummer ABIN667515

Produktdetails

Target: DCUN1D2 (DCN1, Defective in Cullin Neddylation 1, Domain Containing 2 (DCUN1D2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-259

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DCUN1D2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: DCUN1D2, 1-259aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: DCUN1D2 (DCN1, Defective in Cullin Neddylation 1, Domain Containing 2 (DCUN1D2))

Andere Bezeichnung: DCUN1D2 (DCUN1D2 Produkte)

Synonyme: C13orf17 Protein, RGD1311743 Protein, AW495713 Protein, mFLJ10704 Protein, defective in cullin neddylation 1 domain containing 2 Protein, DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) Protein, DCUN1D2 Protein, Dcun1d2 Protein

Hintergrund: DCN1-like protein 2, also known as DCUN1D2, which contains one DCUN1 domain and 1 UBA-like domain, may play a role in the neddylation of cullins that regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 exists on human chromosome 13. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Recombinant human DCUN1D2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: defective in cullin neddylation protein 1(DCN1)-like protein 2, DCUN1L2. NCBI no.: NP_001014305

Molekulargewicht: 32.3kDa (279aa), confirmed by MALDI-TOF