AKR1C4 Protein (AA 1-323) (His tag)

Produktnummer ABIN667485

Produktdetails

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-323

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses AKR1C4 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: AKR1C4, 1-323aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Lagerung: 4 °C

Antigendetails

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Andere Bezeichnung: AKR1C4 (AKR1C4 Produkte)

Synonyme: 3-alpha-HSD Protein, C11 Protein, CDR Protein, CHDR Protein, DD-4 Protein, DD4 Protein, HAKRA Protein, aldo-keto reductase family 1 member C4 Protein, AKR1C4 Protein

Hintergrund: AKR1C4 belongs to aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. It catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. Recombinant human AKR1C4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Aldo-keto reductase family 1 member C4, DHEA-ST, DHEAS, HST, hSTa, ST2, ST2A1, ST2A3. NCBI no.: NP_001809

Molekulargewicht: 39.2 kDa(343aa), confirmed by MALDI-TOF

Pathways: Steroid Hormone Biosynthesis