TAGLN2 Protein (AA 13-199) (His tag)

Produktnummer ABIN667368

Produktdetails

Target: TAGLN2 (Transgelin 2 (TAGLN2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 13-199

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TAGLN2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: TAGLN2, 13-199aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: TAGLN2 (Transgelin 2 (TAGLN2))

Andere Bezeichnung: TAGLN2 (TAGLN2 Produkte)

Synonyme: MGC53739 Protein, MGC75598 Protein, 2700094C18Rik Protein, SM22beta Protein, Sm22B Protein, Sm22a Protein, HA1756 Protein, transgelin 2 Protein, transgelin 2 S homeolog Protein, TAGLN2 Protein, tagln2.S Protein, tagln2 Protein, Tagln2 Protein

Hintergrund: TAGLN2, also known transgelin 2, is one of the earliest markers of differentiated smooth muscle. This protein contains a calponin like repeat and a calponin-homology (CH) domain. It is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. It also binds actin, causing actin fibers to gel within minutes of binding. Binding of transgelin to actin occurs at a ratio of 1:6 actin monomers. Recombinant human TAGLN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Transgelin-2, HA1756, KIAA0120. NCBI no.: NP_003555

Molekulargewicht: 23.4 kDa (208aa), confirmed by MALDI-TOF