DNAJC19 Protein (AA 19-116) (His tag)

Produktnummer ABIN667349

Produktdetails

Target: DNAJC19 (DnaJ (Hsp40) Homolog, Subfamily C, Member 19 (DNAJC19))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-116

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DNAJC19 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: DNAJC19, 19-116aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: DNAJC19 (DnaJ (Hsp40) Homolog, Subfamily C, Member 19 (DNAJC19))

Andere Bezeichnung: DNAJC19 (DNAJC19 Produkte)

Synonyme: PAM18 Protein, TIM14 Protein, TIMM14 Protein, 1810055D05Rik Protein, AA959924 Protein, Tim14 Protein, zgc:73251 Protein, DNAJC19 Protein, DKFZp469M2132 Protein, Gm15118 Protein, RGD1560220 Protein, DnaJ heat shock protein family (Hsp40) member C19 Protein, DnaJ (Hsp40) homolog, subfamily C, member 19 Protein, DnaJ heat shock protein family (Hsp40) member C19 L homeolog Protein, Pam18p Protein, DnaJ heat shock protein family (Hsp40) member C19, pseudogene Protein, DNAJC19 Protein, Dnajc19 Protein, dnajc19 Protein, dnajc19.L Protein, PAM18 Protein, Dnajc19-ps Protein

Hintergrund: DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14. NCBI no.: NP_660304

Molekulargewicht: 15.1 kDa (135aa), confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interaktom