MLF1 Protein (AA 1-268) (His tag)

Produktnummer ABIN667346

Produktdetails

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-268

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MLF1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: MLF1, 1-268aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl

Lagerung: 4 °C

Antigendetails

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Andere Bezeichnung: MLF1 (MLF1 Produkte)

Synonyme: MLF1 Protein, HLS7 Protein, myeloid leukemia factor 1 Protein, myeloid leukemia factor 1 L homeolog Protein, MLF1 Protein, mlf1.L Protein, mlf1 Protein, Mlf1 Protein

Hintergrund: MLF1 (Myeloid leukemia factor 1) belongs to MLF family, and is a widely expressed negative regulator of cell cycle progression functioning upstream of the tumor suppressor p53. This protein interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 normally functions in multi-potent progenitor cells, and its dysregulation may be somewhat responsible for leukemogenesis. Recombinant human MLF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Myeloid leukemia factor 1,. NCBI no.: NP_071888

Molekulargewicht: 32.8kDa (288aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)