NMI Protein (AA 1-307) (His tag)

Produktnummer ABIN667326

Produktdetails

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-307

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NMI Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: NMI, 1-307aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Andere Bezeichnung: NMI (NMI Produkte)

Synonyme: fj02e01 Protein, wu:fj02e01 Protein, NMI Protein, MGC108489 Protein, N-myc and STAT interactor Protein, N-myc (and STAT) interactor Protein, N-myc and STAT interactor L homeolog Protein, NMI Protein, Nmi Protein, nmi Protein, nmi.L Protein

Hintergrund: N-myc-interactor, also known as NMI, is a member of the oncogene Myc family. The Myc family of oncogenes is thought to play an important role in cell proliferation, differentiation, and neoplastic transformation. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Recombinant human NMI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: N-myc-interactor,. NCBI no.: NP_004679

Molekulargewicht: 37.2 kDa (327aa), confirmed by MALDI-TOF