BPHL Protein (AA 38-291) (His tag)

Produktnummer ABIN667322

Produktdetails

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 38-291

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BPHL Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: BPHL, 38-291aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 50mM NaCl

Lagerung: 4 °C

Antigendetails

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Andere Bezeichnung: BPHL (BPHL Produkte)

Synonyme: 2010012D11Rik Protein, 5730533B08Rik Protein, AI115341 Protein, BPH-RP Protein, MCNAA Protein, VACVASE Protein, biphenyl hydrolase like Protein, biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen) Protein, Bphl Protein, BPHL Protein

Hintergrund: BPHL is a Serine hydrolase which Belongs to the AB hydrolase superfamily. This family catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. This protein is expressed at high levels in liver and kidney and at lower levels in heart, intestine and skeletal muscle. It plays a role in detoxification processes. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. Recombinant human BPHL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Valacyclovir hydrolase, BPH-RP, MCNAA, VACVASE. NCBI no.: NP_004323

Molekulargewicht: 31.1kDa (275aa), confirmed by MALDI-TOF