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PMM2 Protein (AA 1-246) (His tag)

PMM2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS – PAGE SDS
Produktnummer ABIN667222
  • Target Alle PMM2 Proteine anzeigen
    PMM2 (Phosphomannomutase 2 (PMM2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-246
    Spezies
    • 6
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses PMM2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    PMM2, 1-246aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS – PAGE
    Top Product
    Discover our top product PMM2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
    Lagerung
    4 °C
  • Target
    PMM2 (Phosphomannomutase 2 (PMM2))
    Andere Bezeichnung
    PMM2 (PMM2 Produkte)
    Synonyme
    cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein
    Hintergrund
    PMM2, also known as Phosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. Recombinant human PMM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDG1, CDG1a, CDGS, Phosphomannomutase 2. NCBI no.: NP_000294
    Molekulargewicht
    30.2 kDa (266aa), confirmed by MALDI-TOF
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