Annexin VIII Protein (AA 1-327) (His tag)

Produktnummer ABIN667190

Produktdetails

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-327

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Annexin VIII Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ANXA8, 1-327aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 1mM EDTA, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Andere Bezeichnung: ANXA8 (ANXA8 Produkte)

Synonyme: ANX8 Protein, ANXA8L1 Protein, ANXA8L2 Protein, AI466995 Protein, Anx8 Protein, anx8 Protein, MGC85309 Protein, ANXA8 Protein, annexin A8 Protein, annexin A8 S homeolog Protein, ANXA8 Protein, Anxa8 Protein, anxa8.S Protein, LOC694628 Protein, LOC100052045 Protein

Hintergrund: ANXA8, also known as Annexin A8, a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Where co-expressed in the same tissues, ANXA8 is often expressed at a 100-fold lower level than Annexin A5. However, ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate to its role in hematopoietic cell differentiation. Recombinant human ANXA8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ANX8, Annexin-8, Annexin VII, Vascular anticoagulant-beta, VAC-beta, Annexin A8. NCBI no.: NP_001035173

Molekulargewicht: 39.0 kDa (347aa), confirmed by MALDI-TOF