TSTA3 Protein (AA 1-321) (His tag)

Produktnummer ABIN667170

Produktdetails

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-321

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TSTA3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: TSTA3, 1-321aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl

Lagerung: 4 °C

Antigendetails

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Andere Bezeichnung: TSTA3 (TSTA3 Produkte)

Synonyme: FX Protein, P35B Protein, SDR4E1 Protein, AI256181 Protein, Tstap35b Protein, p35b Protein, sdr4e1 Protein, TSTA3 Protein, zgc:101805 Protein, si:dkey-235d18none Protein, Fx Protein, tissue specific transplantation antigen P35B Protein, tissue specific transplantation antigen P35B L homeolog Protein, TSTA3 Protein, Tsta3 Protein, tsta3 Protein, tsta3.L Protein

Hintergrund: TSTA3 is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. Recombinant human TSTA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FX, P35B, SDR4E1, GDP-L-fucose synthase. NCBI no.: NP_003304

Molekulargewicht: 38.0 kDa (341aa) confirmed by MALDI-TOF