UBE2B
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS
UBE2B, also known as ubiquitin-conjugating enzyme E2 B, belongs to E2 ubiquitin-conjugating enzyme family. This protein catalyzes the covalent attachment of ubiquitin to other proteins, and associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. It is required for postreplication repair of UV-damaged DNA. It may be involved in neurite outgrowth. Recombinant human UBE2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: E2-17kDa, HHR6B, HR6B, RAD6B, UBC2, Ubiquitin-conjugating enzyme E2B hHR6B, RAD6 homolog B, Ubiquitin carrier protein B, Ubiquitin conjugating enzyme E2 B, Ubiquitin protein ligase B, Ubiquitin-conjugating enzyme E2 17 kDa. NCBI no.: NP_003328