UBE2B Protein (AA 1-152) (His tag)

Produktnummer ABIN667135

Produktdetails

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-152

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: UBE2B, 1-152aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Andere Bezeichnung: UBE2B (UBE2B Produkte)

Synonyme: E2-17kDa Protein, HHR6B Protein, HR6B Protein, RAD6B Protein, UBC2 Protein, e2-17kda Protein, hhr6b Protein, hr6b Protein, rad6b Protein, ubc2 Protein, zgc:100921 Protein, 2610301N02Rik Protein, E2-14k Protein, Rad6b Protein, mHR6B Protein, ubiquitin conjugating enzyme E2 B Protein, ubiquitin-conjugating enzyme E2B Protein, ubiquitin-conjugating enzyme E2B (RAD6 homolog) Protein, ubiquitin conjugating enzyme E2 B S homeolog Protein, UBE2B Protein, Ube2b Protein, ube2b Protein, ube2b.S Protein

Substanzklasse: Viral Protein

Hintergrund: UBE2B, also known as ubiquitin-conjugating enzyme E2 B, belongs to E2 ubiquitin-conjugating enzyme family. This protein catalyzes the covalent attachment of ubiquitin to other proteins, and associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. It is required for postreplication repair of UV-damaged DNA. It may be involved in neurite outgrowth. Recombinant human UBE2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: E2-17kDa, HHR6B, HR6B, RAD6B, UBC2, Ubiquitin-conjugating enzyme E2B hHR6B, RAD6 homolog B, Ubiquitin carrier protein B, Ubiquitin conjugating enzyme E2 B, Ubiquitin protein ligase B, Ubiquitin-conjugating enzyme E2 17 kDa. NCBI no.: NP_003328

Molekulargewicht: 21.4 kDa (188aa), confirmed by MALDI-TOF