TGFBI Protein

Produktnummer ABIN667042

Produktdetails

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: BIGH3 , Fasciclin domain 4 (502-636aa) Human, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris pH8.0 Molecular Weight: 14.5 kDa (135 a.a, residues 502-636)

Lagerung: 4 °C

Antigendetails

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Andere Bezeichnung: BIGH3 (TGFBI Produkte)

Synonyme: TGFBI Protein, BIGH3 Protein, CDB1 Protein, CDG2 Protein, CDGG1 Protein, CSD Protein, CSD1 Protein, CSD2 Protein, CSD3 Protein, EBMD Protein, LCD1 Protein, 68kDa Protein, AI181842 Protein, AI747162 Protein, Beta-ig Protein, big-h3 Protein, Big-h3 Protein, MP70 Protein, MP78 Protein, hm:zeh0933 Protein, wu:fa13f05 Protein, zgc:110495 Protein, transforming growth factor beta induced Protein, transforming growth factor, beta induced Protein, transforming growth factor, beta-induced Protein, TGFBI Protein, Tgfbi Protein, tgfbi Protein

Hintergrund: BIGH3, also known as TGFBI and betaig-h3, is an extracellular matrix protein induced by transforming growth factor(TGF)-beta 1. BIGH3 protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of BIGH3 were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain). Recombinant human BIGH3 protein (fourth FAS domain) was expressed in E. coli and purified by using conventional chromatography techniques. Synonyms: TGFBI, BIGH3, BIGH3, Fasciclin domain 4, Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, Transforming growth factor-beta-induced protein ig-h3, RGD containing collagen associated protein, Beta ig h3, AI747162, big h3, CSD3, Kerato epithelin, LCD1, MGC150270, RGD CAP, TGFBI transforming growth factor, beta induced, 68kDa, AI181842, Beta ig, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, EBMD, Transforming growth factor beta induced protein ig h3. NCBI no.: NP_000349

Molekulargewicht: 14.5 kDa (135 aa), confirmed by MALDI-TOF.