Fission 1 Protein (FIS1) (AA 1-122) (His tag)

Produktnummer ABIN666999

Produktdetails

Target: Fission 1 (FIS1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-122

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Fission 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: TTC11, 1-122aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: Fission 1 (FIS1)

Andere Bezeichnung: TTC11 (FIS1 Produkte)

Synonyme: TTC11 Protein, 2010003O14Rik Protein, Ttc11 Protein, fission, mitochondrial 1 Protein, FIS1 Protein, Fis1 Protein

Hintergrund: TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission. Recombinant human TTC11, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: FIS1, Tetratricopeptide repeat domain 11 2010003O14Rik, CGI 135, CGI135, FIS 1, Fis1 homolog, FIS1, S, cerevisiae, homolog of, Fission 1 (mitochondrial outer membrane) homolog, Fission 1 (mitochondrial outer membrane) homolog (S, cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast) Fission 1 homolog, H NH0132A01.6, hFis 1, hFis1, Mitochondrial fission 1 protein, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11. NCBI no.: NP_057152

Molekulargewicht: 16.3 kDa(142aa), confirmed by MALDI-TOF

Pathways: Positive Regulation of Endopeptidase Activity