CRNN Protein (AA 1-495) (His tag)

Produktnummer ABIN666956

Produktdetails

Target: CRNN (Cornulin (CRNN))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-495

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CRNN Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: CRNN, 1-495aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: CRNN (Cornulin (CRNN))

Andere Bezeichnung: CRNN (CRNN Produkte)

Synonyme: C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein

Hintergrund: CRNN is a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. It contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This protein, also Known as Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Recombinant CRNN protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DRC1, PDRC1, SEP53, Cornulin 53 kDa putative calcium binding protein, 53 kDa squamous epithelial induced stress protein, 58 kDa heat shock protein, C1orf10, Squamous epithelial heat shock protein 53, Tumor related protein. NCBI no.: AAH30807

Molekulargewicht: 55.7 kDa (515aa)