ALIX Protein (AA 1-392) (His tag)

Produktnummer ABIN666945

Produktdetails

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-392

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ALIX Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Alix, 1-392aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.

Lagerung: 4 °C

Antigendetails

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Andere Bezeichnung: Alix (PDCD6IP Produkte)

Synonyme: DDBDRAFT_0167145 Protein, DDBDRAFT_0185177 Protein, DDB_0167145 Protein, DDB_0185177 Protein, AIP1 Protein, ALIX Protein, DRIP4 Protein, HP95 Protein, AI480591 Protein, AW544830 Protein, Aip1 Protein, Alix Protein, C76364 Protein, Eig2 Protein, mKIAA1375 Protein, CG12876 Protein, DAIP1 Protein, Dmel\\CG12876 Protein, GB11744 Protein, RGD1561176 Protein, zgc:63638 Protein, wu:fb70d03 Protein, wu:fy65h02 Protein, PDCD6IP Protein, aip1 Protein, alix Protein, hp95 Protein, drip4 Protein, ALG-2 interacting protein X Protein, programmed cell death 6 interacting protein Protein, programmed cell death 6-interacting protein Protein, Programmed cell death 6 interacting protein Protein, programmed cell death 6 interacting protein L homeolog Protein, alxA Protein, PDCD6IP Protein, Pdcd6ip Protein, ALiX Protein, LOC412662 Protein, pdcd6ip Protein, Bm1_48390 Protein, pdcd6ip.L Protein

Hintergrund: Alix, also known as PDCD6IP, is a cytoplasmic protein that interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. It’s involved in concentration and sorting of cargo proteins of the multivesicular body for incorporation into intralumenal vesicles that are generated by invagination and scission from the limiting membrane of the endosome. Overexpression of this protein and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death. Recombinant PDCD6IP protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AIP1, PDCD6IP, DRIP4, HP95, PDC6I , Programmed cell death 6 interacting protein ALG 2 interacting protein 1, ALG2 interacting protein X, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, KIAA1375, MGC17003, PDCD6 interacting protein, Programmed cell death 6 interacting protein. NCBI no.: NP_037506

Molekulargewicht: 45.8 kDa (412aa), confirmed by MALDI-TOF.

Pathways: p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation