Glutaredoxin 2 Protein (GRX2) (AA 20-164) (His tag)

Produktnummer ABIN666919

Produktdetails

Target: Glutaredoxin 2 (GRX2)

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-164

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Glutaredoxin 2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Glutaredoxin-2, 20-164aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 0.1 mM PMSF, 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: Glutaredoxin 2 (GRX2)

Andere Bezeichnung: Glutaredoxin-2 (GRX2 Produkte)

Synonyme: ECK1049 Protein, JW1051 Protein, CGI-133 Protein, GRX2 Protein, 1700010P22Rik Protein, AI645710 Protein, Grx2 Protein, glutaredoxin 2 (Grx2) Protein, glutaredoxin Grx2 Protein, thioredoxin Protein, glutaredoxin 2 Protein, glutaredoxin 2 (thioltransferase) Protein, grxB Protein, grx2 Protein, AF_RS10790 Protein, GLRX2 Protein, Glrx2 Protein

Hintergrund: Glutaredoxin-2, as known as GRX2, multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase(GST) activity. This protein is localized both in the mitochondria and nucleus. It has anti-apoptotic activity by preventing cardiolipin oxidation and cytochrome c release. GRX2 exhibited 36% identity with GRX1 and had a disulfide active center containing the Cys-Ser-Tyr-Cys motif. Recombinant human Glutaredoxin 2, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: GLRX2, GRX2, CGI133. NCBI no.: NP_932066

Molekulargewicht: 17.0 kDa (154aa), confirmed by MALDI-TOF.

Pathways: Cell RedoxHomeostasis