RRAS2 Protein (AA 1-201) (His tag)

Produktnummer ABIN666896

Produktdetails

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-201

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RRAS2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: RRAS2, 1- 201 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA

Lagerung: 4 °C

Antigendetails

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Andere Bezeichnung: RRAS2 (RRAS2 Produkte)

Synonyme: TC21 Protein, 2610016H24Rik Protein, C86394 Protein, Ras-related protein R-Ras2 Protein, RAS related 2 Protein, related RAS viral (r-ras) oncogene 2 Protein, related RAS viral (r-ras) oncogene homolog 2 Protein, TVAG_453070 Protein, Bm1_46660 Protein, RRAS2 Protein, Rras2 Protein

Hintergrund: RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like GTPase family that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. It is implicated in the pathogenesis of human cancers. Thus, overexpression of active RRAS2 in EpH4 cells induces tumorigenicity through the phosphoinositide 3-kinase, p38 MAPK, and mTOR pathways, and these cells lose their sensitivity to the normal growth inhibitory role of TGF-beta. Recombinant human RRAS2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TC21, RAS viral (r-ras) oncogene homolog 2 isoform a C86394, Oncogene RRAS2, Oncogene TC21, Ras like protein TC21, Ras related protein R Ras2, Related RAS viral (r ras) oncogene homolog 2, Related RAS viral oncogene homolog 2, RRAS 2, TC 21, Teratocarcinoma oncogene, Teratocarcinoma oncogene TC21. NCBI no.: NP_036382

Molekulargewicht: 25.2 kDa (221aa), confirmed by MALDI-TOF.