GDF5 Protein (AA 382-501) (His tag)

Produktnummer ABIN666773

Produktdetails

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 382-501

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GDF5 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: GDF-5, 382-501aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 10 mM Sodium citrate pH 3.5, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF-5 (GDF5 Produkte)

Synonyme: CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein

Hintergrund: Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Growth differentiation factor 5, BMP14, CDMP1, LAP4, OS5, SYNS2, Growth differentiation factor 5 Cartilage derived morphogenetic protein 1,. NCBI no.: NP_000548

Molekulargewicht: 15.8 kDa (141aa), confirmed by MALDI-TOF.