Complexin 1 Protein (CPLX1) (AA 1-134) (His tag)

Produktnummer ABIN666720

Produktdetails

Target: Complexin 1 (CPLX1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-134

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Complexin 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Complexin1, 1-134aa, Human, His tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: Complexin 1 (CPLX1)

Andere Bezeichnung: Complexin1 (CPLX1 Produkte)

Synonyme: MGC84299 Protein, CPLX1 Protein, CPX-I Protein, CPX1 Protein, 921-S Protein, complexin 1 L homeolog Protein, complexin 1 Protein, cplx1.L Protein, CPLX1 Protein, cplx1 Protein, Cplx1 Protein

Hintergrund: Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPXL1, CPX1, Synaphin-2, Complexin 1, Complexin I, CPX1, Synaphin 2,. NCBI no.: NP_006642

Molekulargewicht: 17.1 kDa (154 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport