CX3CL1 Protein (AA 25-100) (His tag)

Produktnummer ABIN666659

Produktdetails

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-100

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CX3CL1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: CX3CL1/Fractalkine, 25- 100 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In Phosphate buffered saline (pH7.4), 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Andere Bezeichnung: CX3CL1/Fractalkine (CX3CL1 Produkte)

Synonyme: ABCD3 Protein, CX3CL1 Protein, DKFZp459K117 Protein, Cx3c Protein, Scyd1 Protein, ABCD-3 Protein, C3Xkine Protein, CXC3 Protein, CXC3C Protein, NTN Protein, NTT Protein, SCYD1 Protein, fractalkine Protein, neurotactin Protein, AB030188 Protein, AI848747 Protein, CX3C Protein, Cxc3 Protein, D8Bwg0439e Protein, ATP binding cassette subfamily D member 3 Protein, C-X3-C motif chemokine ligand 1 Protein, chemokine (C-X3-C motif) ligand 1 Protein, ABCD3 Protein, CX3CL1 Protein, Cx3cl1 Protein, Abcd3 Protein

Hintergrund: CX3CL1, also known as fractalkine. CX3CL1 has a unique CX3C cysteine motif near the amino terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucin like stalk. It is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Also, CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Recombinant human CX3CL1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, CX3CL1 , Chemokine (C-X3-C motif) ligand 1, small inducible cytokine subfamily D (Cys-X3-Cys) member 1 (fractalkine, neurotactin), fractalkine, neurotactin. NCBI no.: NP_002987

Molekulargewicht: 10.9 kDa (97aa), confirmed by MALDI-TOF.

Pathways: Synaptic Membrane