Peroxiredoxin 2 Protein (PRDX2) (AA 1-198) (His tag)

Produktnummer ABIN6388119

Produktdetails

Target: Peroxiredoxin 2 (PRDX2)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 1-198

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Peroxiredoxin 2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSHMASGNA QIGKSAPDFT ATAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN

Reinheit: > 90 % by SDS - PAGE

Biological Activity Comment: Specific activity is > 700 pmol/min/ug, Activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Bioactivity Validated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % Glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Peroxiredoxin 2 (PRDX2)

Andere Bezeichnung: Prdx2 (PRDX2 Produkte)

Synonyme: NKEF-B Protein, NKEFB Protein, PRP Protein, PRX2 Protein, PRXII Protein, PTX1 Protein, TDPX1 Protein, TPX1 Protein, TSA Protein, AL022839 Protein, Band-8 Protein, NkefB Protein, PrxII Protein, TDX1 Protein, TPx Protein, TPx-B Protein, TR Protein, Tdpx1 Protein, Torin Protein, nkefb Protein, prx-2 Protein, prx2 Protein, prxii Protein, tdpx1 Protein, tpx1 Protein, peroxiredoxin 2 Protein, peroxiredoxin 2 L homeolog Protein, PRDX2 Protein, Prdx2 Protein, prdx2.L Protein

Hintergrund: Prdx2, also known as peroxiredoxin-2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Prdx2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Prdx2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant mouse Prdx2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 24.3 kDa (222aa) Confirmed by MALDI-TOF

NCBI Accession: NP_035693

UniProt: Q61171