BTN3A1 Protein (AA 30-254) (hIgG-His-tag)

Produktnummer ABIN6388072

Produktdetails

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-254

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses BTN3A1 Protein ist gelabelt mit hIgG-His-tag.

Applikation: SDS-PAGE (SDS)

Sequenz: QFSVLGPSGP ILAMVGEDAD LPCHLFPTMS AETMELKWVS SSLRQVVNVY ADGKEVEDRQ SAPYRGRTSI LRDGITAGKA ALRIHNVTAS DSGKYLCYFQ DGDFYEKALV ELKVAALGSD LHVDVKGYKD GGIHLECRST GWYPQPQIQW SNNKGENIPT VEAPVVADGV GLYAVAASVI MRGSSGEGVS CTIRSSLLGL EKTASISIAD PFFRSAQRWI AALAGLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Andere Bezeichnung: BTN3A1 (BTN3A1 Produkte)

Synonyme: BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein

Hintergrund: BTN3A1, also known as butyrophilin subfamily 3 member A1 isoform, belongs to the immunoglobulin superfamily. It is composed of an extracellular N-terminal IgV and a membrane proximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. This protein plays a role in T-cell activation and in the adaptive immune response. Also, it regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Recombinant human BTN3A1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 51.1kDa (464aa) 50-70kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_008979

UniProt: O00481

Pathways: Activated T Cell Proliferation