Relaxin 2 Protein (RLN2) (AA 25-185) (His tag)

Produktnummer ABIN6387989

Produktdetails

Target: Relaxin 2 (RLN2)

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-185

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses Relaxin 2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH

Reinheit: > 85 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Relaxin 2 (RLN2)

Andere Bezeichnung: RLN2 (RLN2 Produkte)

Synonyme: H2 Protein, H2-RLX Protein, RLXH2 Protein, bA12D24.1.1 Protein, bA12D24.1.2 Protein, RFLX Protein, rln2 Protein, rln3c Protein, rlx3c Protein, si:rp71-39b20.5 Protein, relaxin 2 Protein, insulin-like 3 (Leydig cell) Protein, RLN2 Protein, insl3 Protein

Hintergrund: RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18 kDa in size and 185 aa in length. It contains a 24 aa signal sequence, a 3.3 kDa, 29 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2.7 kDa, 24 aa A domain. Recombinant human RLN2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 19.3kDa (170aa) 18-28kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_604390

UniProt: P04090

Pathways: Hormone Activity