Crystallography grade
ADAM10
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA, Crys
Crystallography grade
ADAM10
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA, Crys
ADAM10 Protein, Adam10 Protein, adam10 Protein, wu:fc03d12 Protein, ad10 Protein, cd156c Protein, kuz Protein, kuzbanian Protein, madm Protein, xadam10 Protein, ADAM-10 Protein, ADAM 10 Protein, AD10 Protein, CD156c Protein, HsT18717 Protein, MADM Protein, 1700031C13Rik Protein, LOC100219653 Protein, zgc:64203 Protein, ADAM metallopeptidase domain 10 Protein, ADAM metallopeptidase domain 10a Protein, ADAM metallopeptidase domain 10 S homeolog Protein, a disintegrin and metallopeptidase domain 10 Protein, ADAM metallopeptidase domain 10b Protein, ADAM10 Protein, Adam10 Protein, adam10a Protein, adam10.S Protein, adam10b Protein
Hintergrund
ADAM10, as known as disintegrin and metalloproteinase domain-containing protein 10 isoform 1, is a member of the ADAM family that contains a disintegrin and metallogrotease-like domain. This protein is a sheddase, and has a broad specificity for peptide hydrolysis reactions. Also, it cleaves ephrin, within the ephrin/eph complex, formed between two cell surfaces. When ephrin is freed from the opposing cell, the entire ephrin/eph complex is endocytosed. In neurons, ADAM10 is the most important enzyme with alpha-secretase activity for proteolytic processing of the amyloid precursor protein. Recombinant human ADAM10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molekulargewicht
51.6kDa (467aa) 50-70kDa (SDS-PAGE under reducing conditions.)