NAGA Protein (AA 18-411) (His tag)

Produktnummer ABIN6387829

Produktdetails

Target: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 18-411

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses NAGA Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: LDNGLLQTPP MGWLAWERFR CNINCDEDPK NCISEQLFME MADRMAQDGW RDMGYTYLNI DDCWIGGRDA SGRLMPDPKR FPHGIPFLAD YVHSLGLKLG IYADMGNFTC MGYPGTTLDK VVQDAQTFAE WKVDMLKLDG CFSTPEERAQ GYPKMAAALN ATGRPIAFSC SWPAYEGGLP PRVNYSLLAD ICNLWRNYDD IQDSWWSVLS ILNWFVEHQD ILQPVAGPGH WNDPDMLLIG NFGLSLEQSR AQMALWTVLA APLLMSTDLR TISAQNMDIL QNPLMIKINQ DPLGIQGRRI HKEKSLIEVY MRPLSNKASA LVFFSCRTDM PYRYHSSLGQ LNFTGSVIYE AQDVYSGDII SGLRDETNFT VIINPSGVVM WYLYPIKNLE MSQQHHHHHH

Reinheit: > 90 % by SDS - PAGE.

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Andere Bezeichnung: NAGA (NAGA Produkte)

Synonyme: D22S674 Protein, GALB Protein, alpha-N-acetylgalactosaminidase Protein, N-acetyl galactosaminidase, alpha Protein, Naga Protein, NAGA Protein

Hintergrund: NAGA, also known as alpha-N-acetylgalactosaminidase, is a lysosomal exoglycosidase that cleaves terminal alpha-N-acetylgalactosamine residues from glycopeptides and glycolipids. It is hardly expected to cause an allergic reaction in Fabry disease patients. It is highly promising as a new and safe enzyme for ERT for Fabry disease. Recombinant human NAGA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 45.5kDa (400aa) 40-57kDa (SDS-PAGE under reducing conditions

NCBI Accession: NP_000253

UniProt: P17050