SPOCK3 Protein (AA 22-436) (His tag)

Produktnummer ABIN6387812

Produktdetails

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-436

Spezies: Maus

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses SPOCK3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: AAAAVAVAGG RSDGGNFLDE KQWLTTISQY DKEVGQWNKF RDEVEDDYFR TWNPGKPFDQ ALDPAKDPCL KTKCSRHKVC ITQDAQTALC ISHRRLTHSM KEVGGSHKQW RGLPSSTCKP CPIAYASPVC GSDGHSYSSQ CKLEYQACVL GKQISIKCEG RCPCPSDKSM NIGRNVKRAC SDLEFREVAN RLRDWFKALH ESGSQNKKTK ALLRPERSRF DTSILPICKD SLGWMFNRLD TNYDLLLDQS ELGSIYLDKN EQCTKAFFNS CDTYKDSLIS NNEWCYCFQR QQDPPCHTEL SNIQKRQGIK KLLGQYIPLC DEDGYYKPTQ CHGSVGQCWC VDRYGNEVVG SRINGVADCA IDFEISGDFA SGDFREWTDD EGEEDDIMND KDDIEDDDED EGDDDDDGDV HDGYILEHHH HHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Andere Bezeichnung: Spock3 (SPOCK3 Produkte)

Synonyme: im:7139568 Protein, si:dkey-285b22.1 Protein, HSAJ1454 Protein, TES-3 Protein, TICN3 Protein, Testican-3 Protein, 2900045C01Rik Protein, AI428471 Protein, mKIAA4039 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 Protein, spock3 Protein, SPOCK3 Protein, Spock3 Protein

Hintergrund: Spock3, also known as testican-3, is a nervous system-expressed heparan sulfate proteoglycan belonging to a subgroup of the BM-40/SPARC/osteonectin family, the role of which in brain development is unclear. It inhibits the processing of pro-matrix metalloproteinase 2(MMP-2) by MT1-MMP and MT3-MMP. It is mostly confined to the developmental stage of the brain. Recombinant mouse Spock3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 47.9kDa (423aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_001239549

UniProt: Q8BKV0

Pathways: Glycosaminoglycan Metabolic Process