NAPSA Protein (AA 64-420) (His tag)

Produktnummer ABIN6387805

Produktdetails

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 64-420

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NAPSA Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSKPIFVPL SNYRDVQYFG EIGLGTPPQN FTVAFDTGSS NLWVPSRRCH FFSVPCWLHH RFDPKASSSF QANGTKFAIQ YGTGRVDGIL SEDKLTIGGI KGASVIFGEA LWEPSLVFAF AHFDGILGLG FPILSVEGVR PPMDVLVEQG LLDKPVFSFY LNRDPEEPDG GELVLGGSDP AHYIPPLTFV PVTVPAYWQI HMERVKVGPG LTLCAKGCAA ILDTGTSLIT GPTEEIRALH AAIGGIPLLA GEYIILCSEI PKLPAVSFLL GGVWFNLTAH DYVIQTTRNG VRLCLSGFQA LDVPPPAGPF WILGDVFLGT YVAVFDRGDM KSSARVGLAR ARTRGADLGW GETAQAQFPG

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl (  pH 8.0) containing 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Andere Bezeichnung: NAPSA (NAPSA Produkte)

Synonyme: KAP Protein, Kdap Protein, NAP1 Protein, NAPA Protein, SNAPA Protein, pronapsin Protein, kap Protein, kdap Protein, nap1 Protein, napa Protein, napsa Protein, snapa Protein, napsin A aspartic peptidase Protein, napsin A aspartic peptidase L homeolog Protein, NAPSA Protein, Napsa Protein, napsa.L Protein

Hintergrund: NAPSA, also known as Napsin-A, belongs to the peptidase A1 family and may be involved in processing of pneumocyte surfactant precursors. The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. Recombinant human NAPSA, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography.

Molekulargewicht: 40.9 kDa (380 aa) confirmed by MALDI-TOF

NCBI Accession: NP_004842

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis