SSR1 Protein (AA 22-207) (His tag)

Produktnummer ABIN6387332

Produktdetails

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-207

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SSR1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSRGGPRGL LAVAQDLTED EETVEDSIIE DEDDEAEVEE DEPTDLVEDK EEEDVSGEPE ASPSADTTIL FVKGEDFPAN NIVKFLVGFT NKGTEDFIVE SLDASFRYPQ DYQFYIQNFT ALPLNTVVPP QRQATFEYSF IPAEPMGGRP FGLVINLNYK DLNGNVFQDA VFNQTVTVIE REDGLDGET

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 20 % glycerol, 0.1M NaCl, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Andere Bezeichnung: SSR1 (SSR1 Produkte)

Synonyme: cb758 Protein, trapa Protein, Ssr1 Protein, TRAPA Protein, 2510001K09Rik Protein, 6330400D04 Protein, AI159733 Protein, AI452176 Protein, SSR Protein, signal sequence receptor, alpha Protein, signal sequence receptor, alpha (translocon-associated protein alpha) Protein, signal sequence receptor subunit 1 Protein, signal sequence receptor, alpha (translocon-associated protein alpha) S homeolog Protein, ssr1 Protein, SSR1 Protein, Ssr1 Protein, ssr1.S Protein

Hintergrund: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Recombinant human SSR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 23.1kDa (209aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_003135

UniProt: P43307

Pathways: ER-Nucleus Signaling