MARCKSL1 Protein (AA 1-195) (His tag)

Produktnummer ABIN6387162

Produktdetails

Target: MARCKSL1 (MARCKS-Like 1 (MARCKSL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-195

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MARCKSL1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMGSQSSK APRGDVTAEE AAGASPAKAN GQENGHVKSN GDLSPKGEGE SPPVNGTDEA AGATGDAIEP APPSQGAEAK GEVPPKETPK KKKKFSFKKP FKLSGLSFKR NRKEGGGDSS ASSPTEEEQE QGEIGACSDE GTAQEGKAAA TPESQEPQAK GAEASAASEE EAGPQATEPS TPSGPESGPT PASAEQNE

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 20 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: MARCKSL1 (MARCKS-Like 1 (MARCKSL1))

Andere Bezeichnung: MARCKSL1 (MARCKSL1 Produkte)

Synonyme: F52 Protein, MACMARCKS Protein, MLP Protein, MLP1 Protein, MRP Protein, AL022768 Protein, AW215397 Protein, AW536807 Protein, D4Bc1 Protein, MacMARCKS Protein, Macs2 Protein, Macs3 Protein, Mlp Protein, Mrp Protein, cb575 Protein, marcks1 Protein, marcksl1 Protein, sb:cb575 Protein, wu:fa66h03 Protein, wu:fj18a04 Protein, zgc:65840 Protein, MARCKSL1 Protein, f52 Protein, mlp Protein, mrp Protein, mlp1 Protein, macmarcks Protein, XMLP Protein, MARCKS like 1 Protein, MARCKS-like 1 Protein, MARCKS-like 1a Protein, MARCKS-like 1 L homeolog Protein, MARCKS-related protein Protein, MARCKS-like 1 S homeolog Protein, MARCKSL1 Protein, Marcksl1 Protein, marcksl1a Protein, marcksl1 Protein, marcksl1.L Protein, mrp Protein, marcksl1.S Protein

Hintergrund: MARCKS-related protein, also known as MARCKSL1, is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indicator of PKC activation. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading. Recombinant human MARCKSL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 21.9kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_075385

UniProt: P49006