DNAJB11 Protein (AA 23-358) (His tag)

Produktnummer ABIN667400

Produktdetails

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-358

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DNAJB11 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: DNAJB11, 23-358aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Lagerung: 4 °C

Antigendetails

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Andere Bezeichnung: DNAJB11 (DNAJB11 Produkte)

Synonyme: MGC75796 Protein, MGC81924 Protein, ABBP-2 Protein, ABBP2 Protein, DJ9 Protein, Dj-9 Protein, EDJ Protein, ERdj3 Protein, ERj3 Protein, ERj3p Protein, PRO1080 Protein, UNQ537 Protein, hDj-9 Protein, 1810031F23Rik Protein, AL024055 Protein, Dj9 Protein, LRRGT00084 Protein, cb954 Protein, DnaJ heat shock protein family (Hsp40) member B11 Protein, DnaJ heat shock protein family (Hsp40) member B11 S homeolog Protein, DnaJ (Hsp40) homolog, subfamily B, member 11 Protein, dnajb11 Protein, DNAJB11 Protein, dnajb11.S Protein, Dnajb11 Protein

Hintergrund: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. It serves as a co-chaperone for HSPA5 and binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. Recombinant human DNAJB11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DnaJ homolog subfamily B member 11, ABBP-2, ABBP2, DJ9, EDJ, ERdj3, ERj3, hDj9, HEDJ, PRO1080, UNQ537. NCBI no.: NP_057390

Molekulargewicht: 40.5 kDa (357aa), confirmed by MALDI-TOF

Pathways: ER-Nucleus Signaling