TFAM Protein (AA 43-246) (His tag)

Produktnummer ABIN667339

Produktdetails

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Protein-Typ: Recombinant

Proteineigenschaft: AA 43-246

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TFAM Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: TFAM, 43-246aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: TFAM (TFAM Produkte)

Synonyme: tcf6 Protein, mttf1 Protein, mttfa Protein, tcf6l1 Protein, tcf6l2 Protein, tcf6l3 Protein, mttfa-A Protein, xl-mtTFA Protein, MGC153358 Protein, zgc:153358 Protein, MTTF1 Protein, MTTFA Protein, TCF6 Protein, TCF6L1 Protein, TCF6L2 Protein, TCF6L3 Protein, AI661103 Protein, Hmgts Protein, mtTFA Protein, tsHMG Protein, Mttfa Protein, transcription factor A, mitochondrial Protein, transcription factor A, mitochondrial L homeolog Protein, TFAM Protein, tfam.L Protein, tfam Protein, Tfam Protein

Hintergrund: TFAM, also known as MtTF1 or mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. TFAM is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. TFAM has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. Recombinant human TFAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Transcription factor A, mitochondrial precursor, MtTF1, mtTFA, TCF6, TCF6L1, TCF6L2, TCF6L3. NCBI no.: NP_003192

Molekulargewicht: 26.6 kDa (225aa), confirmed by MALDI-TOF

Pathways: Chromatin Binding