CD160 Protein (CD160) (AA 27-159) (Fc Tag)

Produktnummer ABIN6253378

Produktdetails

Target: CD160

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-159

Spezies: Human

Quelle: CHO Cells

Aufreinigungstag / Konjugat: Dieses CD160 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: CD160 (human):Fc (human) (rec.)

Spezifität: The extracellular domain of human CD160 (aa 27-159) is fused to the N-terminus of the Fc region of human IgG1.

Produktmerkmale: Protein. The extracellular domain of human CD160 (aa 27-159) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival.

Reinheit: >98 % (SDS-PAGE)

Endotoxin-Niveau: <0.06EU/μg protein (LAL test, Lonza).

Biological Activity Comment: Measured by its binding ability in a functional ELISA.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from 0.2μm-filtered solution in PBS.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Antigendetails

Target: CD160

Andere Bezeichnung: CD160 (CD160 Produkte)

Synonyme: CD160 Protein, RGD1563598 Protein, BY55 Protein, AU045688 Protein, By55 Protein, NK1 Protein, NK28 Protein, CD160 molecule Protein, CD160 antigen Protein, CD160 Protein, Cd160 Protein

Hintergrund:

Alternate Names/Synonyms: Natural Killer Cell Receptor BY55, NK28, NK1

Product Description: CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival.

NCBI Accession: NP_008984