Glutaredoxin 1 Protein (GRX1) (AA 1-107) (His tag)

Produktnummer ABIN5855036

Produktdetails

Target: Glutaredoxin 1 (GRX1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-107

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Glutaredoxin 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMAQEFVN CKIQSGKVVV FIKPTCPYCR KTQEILSQLP FKQGLLEFVD ITATNNTSAI QDYLQQLTGA RTVPRVFIGK DCIGGCSDLI SMQQTGELMT RLKQIGALQL

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM MES (  pH 5.0) containing 20 % Glycerol, 0.1M NaCl

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Glutaredoxin 1 (GRX1)

Andere Bezeichnung: Glrx (GRX1 Produkte)

Synonyme: Glrx1 Protein, Grx Protein, grx Protein, wu:fc38f02 Protein, zgc:103707 Protein, GLRXL Protein, Grx1 Protein, TTase Protein, C86710 Protein, D13Wsu156e Protein, grx1 Protein, GLRX Protein, GRX Protein, GRX1 Protein, GLRX1 Protein, TTF Protein, glrx Protein, glutaredoxin Protein, glutaredoxin (thioltransferase) Protein, glutaredoxin Grx1 Protein, NrdH-redoxin Protein, Uncharacterized monothiol glutaredoxin F10D7.3 Protein, glutaredoxin-1 (Grx1) Protein, temporal expression: late Protein, glutaredoxin L homeolog Protein, Glrx Protein, glrx Protein, GLRX Protein, grx1 Protein, AF_RS07750 Protein, F10D7.3 Protein, AFUA_1G06100 Protein, NT01EI_2528 Protein, O2L Protein, glrx.L Protein

Substanzklasse: Viral Protein

Hintergrund: Glrx, also known as glutaredoxin-1, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Mammalian Glutaredoxin is known to have two isoforms, GRX1 and GRX2. GRX1 is a cytosolic protein, whereas GRX2 is localized both in the mitochondria and nucleus. Glrx may be involved in a various cellular events such as signal transduction, stress response, and metabolic regulation by regulating the redox status of cellular proteins. Recombinant mouse Glrx protein was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 14.3 kDa (130aa) confirmed by MALDI-TOF

NCBI Accession: NP_444338

UniProt: Q9QUH0

Pathways: Cell RedoxHomeostasis