KIR2DL5A Protein (AA 22-238) (hIgG-His-tag)

Produktnummer ABIN5854937

Produktdetails

Target: KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-238

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses KIR2DL5A Protein ist gelabelt mit hIgG-His-tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPHEGGQDK PLLSAWPSAV VPRGGHVTLL CRSRLGFTIF SLYKEDGVPV PELYNKIFWK SILMGPVTPA HAGTYRCRGS HPRSPIEWSA PSNPLVIVVT GLFGKPSLSA QPGPTVRTGE NVTLSCSSRS SFDMYHLSRE GRAHEPRLPA VPSVNGTFQA DFPLGPATHG GTYTCFGSLH DSPYEWSDPS DPLLVSVTGN SSSSSSSPTE PSSKTGIRRH VEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))

Andere Bezeichnung: KIR2DL5A (KIR2DL5A Produkte)

Synonyme: CD158F Protein, KIR2DL5 Protein, KIR2DL5.1 Protein, KIR2DL5.3 Protein, KIR2DL5B Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A Protein, KIR2DL5A Protein

Hintergrund: KIR2DL5A, also known as killer cell immunoglobulin-like receptor 2DL5A, is a type I transmembrane glycoprotein that belongs to the killer cell Ig-like receptor (KIR) family. It is detected on the cell surface as a monomer that, upon tyrosine phosphorylation, recruits the Src homology region 2-containing protein tyrosine phosphatase-2, It is thus an inhibitory receptor gathering a combination of genetic, structural, and functional features unique among KIR, which suggests that it plays a specialized role in innate immunity. Recombinant human KIR2DL5A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 50.5kDa (459aa) 50-70kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_065396

UniProt: Q8N109