L1CAM Protein (AA 20-1115) (His tag)
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- Target Alle L1CAM Proteine anzeigen
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-1115
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses L1CAM Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- IQIPEELMEP PVITEQSPRR LVVFPTDDIS LKCEASGKPE VQFRWTRDGV HFKPKEELGV TVYQSPHSGS FTITGNNSNF AQRFQGIYRC FASNKLGTAM SHEIRLMAEG APKWPKETVK PVEVEEGESV VLPCNPPPSA EPLRIYWMNS KILHIKQDER VTMGQNGNLY FANVLTSDNH SDYICHAHFP GTRTIIQKEP IDLRVKATNS MIDRKPRLLF PTNSSSHLVA LQGQPLVLEC IAEGFPTPTI KWLRPSGPMP ADRVTYQNHN KTLQLLKVGE EDDGEYRCLA ENSLGSARHA YYVTVEAAPY WLHKPQSHLY GPGETARLDC QVQGRPQPEV TWRINGIPVE ELAKDQKYRI QRGALILSNV QPSDTMVTQC EARNRHGLLL ANAYIYVVQL PAKILTADNQ TYMAVQGSTA YLLCKAFGAP VPSVQWLDED GTTVLQDERF FPYANGTLGI RDLQANDTGR YFCLAANDQN NVTIMANLKV KDATQITQGP RSTIEKKGSR VTFTCQASFD PSLQPSITWR GDGRDLQELG DSDKYFIEDG RLVIHSLDYS DQGNYSCVAS TELDVVESRA QLLVVGSPGP VPRLVLSDLH LLTQSQVRVS WSPAEDHNAP IEKYDIEFED KEMAPEKWYS LGKVPGNQTS TTLKLSPYVH YTFRVTAINK YGPGEPSPVS ETVVTPEAAP EKNPVDVKGE GNETTNMVIT WKPLRWMDWN APQVQYRVQW RPQGTRGPWQ EQIVSDPFLV VSNTSTFVPY EIKVQAVNSQ GKGPEPQVTI GYSGEDYPQA IPELEGIEIL NSSAVLVKWR PVDLAQVKGH LRGYNVTYWR EGSQRKHSKR HIHKDHVVVP ANTTSVILSG LRPYSSYHLE VQAFNGRGSG PASEFTFSTP EGVPGHPEAL HLECQSNTSL LLRWQPPLSH NGVLTGYVLS YHPLDEGGKG QLSFNLRDPE LRTHNLTDLS PHLRYRFQLQ ATTKEGPGEA IVREGGTMAL SGISDFGNIS ATAGENYSVV SWVPKEGQCN FRFHILFKAL GEEKGGASLS PQYVSYNQSS YTQWDLQPDT DYEIHLFKER MFRHQMAVKT NGTGRVRLPP AGFATELEHH HHHH
- Reinheit
- > 90 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product L1CAM Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Andere Bezeichnung
- L1CAM (L1CAM Produkte)
- Synonyme
- l1cam-a Protein, CAML1 Protein, CD171 Protein, HSAS Protein, HSAS1 Protein, MASA Protein, MIC5 Protein, N-CAM-L1 Protein, N-CAML1 Protein, NCAM-L1 Protein, S10 Protein, SPG1 Protein, L1 Protein, Hsas Protein, Hyd Protein, NCAML1 Protein, L1 cell adhesion molecule S homeolog Protein, L1 cell adhesion molecule Protein, l1cam.S Protein, L1CAM Protein, L1cam Protein
- Hintergrund
- L1CAM, also known as neural cell adhesion molecule L1 isoform 3, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. It is now recognized to play a key role in cell migration, adhesion, neurite outgrowth, myelination and neuronal differentiation Overexpression of L1CAM in normal and cancer cells increased motility, enhanced growth rate and promoted cell transformation and tumorigenicity. Recombinant human L1CAM, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 123.6kDa (1104aa) 100-150kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001137435
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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