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ICOSLG Protein (AA 19-256) (hIgG-His-tag)
ICOSLG
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5854908
Produktdetails
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Target
Alle ICOSLG Proteine anzeigen
ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
Protein-Typ
Recombinant
Proteineigenschaft
AA 19-256
Spezies
Alle Spezies für ICOSLG Proteine
Human
Quelle
Alle Expressionssysteme für ICOSLG Proteine
Baculovirus infected Insect Cells
Aufreinigungstag / Konjugat
Dieses ICOSLG Protein ist gelabelt mit hIgG-His-tag.
Applikation
SDS-PAGE (SDS)
Sequenz
ADPDTQEKEV RAMVGSDVEL SCACPEGSRF DLNDVYVYWQ TSESKTVVTY HIPQNSSLEN VDSRYRNRAL MSPAGMLRGD FSLRLFNVTP QDEQKFHCLV LSQSLGFQEV LSVEVTLHVA ANFSVPVVSA PHSPSQDELT FTCTSINGYP RPNVYWINKT DNSLLDQALQ NDTVFLNMRG LYDVVSVLRI ARTPSVNIGC CIENVLLQQN LTVGSQTGND IGERDKITEN PVSTGEKNAA TLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH
Reinheit
> 90 % by SDS - PAGE
Endotoxin-Niveau
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
Andere Bezeichnung
ICOSLG (ICOSLG Produkte )
Synonyme
ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
Hintergrund
ICOSLG, also known as ICOS ligand isoform a, is a number of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. This protein is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells. Its dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. Recombinant human ICOSLG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molekulargewicht
53.7kDa (480aa) 50-70kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_056074
UniProt
O75144
Pathways
Production of Molecular Mediator of Immune Response , Activated T Cell Proliferation
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