CD236/GYPC Protein (AA 1-57) (His tag)

Produktnummer ABIN5854842

Produktdetails

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-57

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses CD236/GYPC Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPMWSTRSP NSTAWPLSLE PDPGMASAST TMHTTTIAEP DPGMSGWPDG RMETSTPTIM HHHHHH

Reinheit: > 95 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Andere Bezeichnung: GYPC (GYPC Produkte)

Synonyme: GPC Protein, glpc Protein, 0610037F22Rik Protein, Cd236r Protein, CD236 Protein, CD236R Protein, GE Protein, GPD Protein, GYPD Protein, PAS-2 Protein, PAS-2' Protein, glycophorin C a Protein, glycophorin C (Gerbich blood group) Protein, Glycophorin-C Protein, glycophorin C Protein, gpca Protein, GYPC Protein, glpc Protein, Gypc Protein

Substanzklasse: Viral Protein

Hintergrund: GYPC, also known as glycophorin-C isoform 1, is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. Recombinant human GYPC protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 7.2kDa (66aa) 18-28KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_002092

UniProt: P04921