Chorionic Gonadotropin, beta Polypeptide 3 (CGB3) (AA 21-165) protein (His tag)

Produktnummer ABIN5854819

Produktdetails

Target: Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-165

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: His tag

Applikation: SDS-PAGE (SDS)

Sequenz: ADPSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQHH HHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)

Andere Bezeichnung: CGB3 (CGB3 Produkte)

Synonyme: CGB3 Protein, CGB5 Protein, CGB7 Protein, CGB8 Protein, hCGB Protein, chorionic gonadotropin beta subunit 3 Protein, CGB3 Protein

Hintergrund: CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Recombinant human CGB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 16.6kDa (154aa) 18-28kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_000728

UniProt: P0DN86