Peroxiredoxin 1 Protein (PRDX1) (AA 1-199) (His tag)

Produktnummer ABIN6387795

Produktdetails

Target: Peroxiredoxin 1 (PRDX1)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 1-199

Spezies: Maus

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses Peroxiredoxin 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVNK SKEYFSKQKL EHHHHHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Biological Activity Comment: Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Bioactivity Validated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Peroxiredoxin 1 (PRDX1)

Andere Bezeichnung: Prdx1 (PRDX1 Produkte)

Synonyme: MSP23 Protein, NKEF-A Protein, NKEFA Protein, PAG Protein, PAGA Protein, PAGB Protein, PRX1 Protein, PRXI Protein, TDPX2 Protein, NkefA Protein, OSF-3 Protein, OSF3 Protein, Paga Protein, PrdxI Protein, PrxI Protein, TDX2 Protein, TPxA Protein, Tdpx2 Protein, prx1 Protein, Hbp23 Protein, MGC80194 Protein, MGC84820 Protein, PRDX1 Protein, msp23 Protein, nkefa Protein, pag Protein, paga Protein, pagb Protein, prx-1 Protein, prxi Protein, tdpx2 Protein, hm:zehl0637 Protein, zgc:110343 Protein, TPX-2 Protein, peroxiredoxin 1 Protein, peroxiredoxin 1 S homeolog Protein, peroxiredoxin-1 pseudogene Protein, PRDX1 Protein, Prdx1 Protein, prdx1.S Protein, prdx1 Protein, LOC100350232 Protein

Hintergrund: Prdx1, also known as peroxiredoxin-1, is an important member of peroxiredoxins (Prdxs) regulating various cellular signaling and differentiation. It confers an aggressive survival phenotype of cancer cells and drug-resistance. This protein is also identified as a red blood cell factor which enhances natural killer (NK) cell activity. Recombinant mouse Prdx1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 23.2kDa (207aa) 18-28KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_035164

UniProt: P35700

Pathways: p53 Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events