UBLCP1 Protein (AA 1-318) (His tag)

Produktnummer ABIN5854204

Produktdetails

Target: UBLCP1 (Ubiquitin-Like Domain Containing CTD Phosphatase 1 (UBLCP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-318

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBLCP1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMALPIIV KWGGQEYSVT TLSEDDTVLD LKQFLKTLTG VLPERQKLLG LKVKGKPAEN DVKLGALKLK PNTKIMMMGT REESLEDVLG PPPDNDDVVN DFDIEDEVVE VENREENLLK ISRRVKEYKV EILNPPREGK KLLVLDVDYT LFDHRSCAET GVELMRPYLH EFLTSAYEDY DIVIWSATNM KWIEAKMKEL GVSTNANYKI TFMLDSAAMI TVHTPRRGLI DVKPLGVIWG KFSEFYSKKN TIMFDDIGRN FLMNPQNGLK IRPFMKAHLN RDKDKELLKL TQYLKEIAKL DDFLDLNHKY WERYLSKKQG Q

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: UBLCP1 (Ubiquitin-Like Domain Containing CTD Phosphatase 1 (UBLCP1))

Andere Bezeichnung: UBLCP1 (UBLCP1 Produkte)

Synonyme: UBLCP1 Protein, DKFZp459P2311 Protein, wu:fb33g09 Protein, zgc:86634 Protein, CPUB1 Protein, 4930527B16Rik Protein, 8430435I17Rik Protein, BC002236 Protein, RGD1310386 Protein, ubiquitin like domain containing CTD phosphatase 1 Protein, ubiquitin-like domain containing CTD phosphatase 1 Protein, ubiquitin like domain containing CTD phosphatase 1 S homeolog Protein, ublcp1 Protein, Ublcp1 Protein, UBLCP1 Protein, ublcp1.S Protein

Hintergrund: UBLCP1 also known as ubiquitin-like domain-containing CTD phosphatase 1. This protein dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome. Recombinant human UBLCP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 39.2kDa (341aa) confirmed by MALDI-TOF

NCBI Accession: NP_659486

UniProt: Q8WVY7