CREBZF Protein (AA 1-354) (His tag)

Produktnummer ABIN5853877

Produktdetails

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-354

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CREBZF Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAA AGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPD WHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQ RFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQAAT KSPRKAAAAA ARLNRLKKKE YVMGLESRVR GLAAENQELR AENRELGKRV QALQEESRYL RAVLANETGL ARLLSRLSGV GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVS VEFCSACARK ASSSLKM

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In PBS buffer (  pH 7.4) containing 20 % glycerol, 1  mM DTT, 0.1  mM PMSF

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Andere Bezeichnung: CREBZF (CREBZF Produkte)

Synonyme: SMILE Protein, ZF Protein, 1110034C16Rik Protein, 6330417B10Rik Protein, LAZip Protein, LAZipII Protein, Zf Protein, RGD1565584 Protein, CREB/ATF bZIP transcription factor Protein, CREBZF Protein, Crebzf Protein

Hintergrund: CREBZF strongly activates transcription when bound to HCFC1. It suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. This protein suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. CREBZF is able to down-regulate expression of some cellular genes in CREBZF-expressing cells. Recombinant human CREBZF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 39.5 kDa (377aa) confirmed by MALDI-TOF

NCBI Accession: NP_001034707

UniProt: Q9NS37