GDI1 Protein (AA 1-447) (His tag)

Produktnummer ABIN5853715

Produktdetails

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-447

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GDI1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMDEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESSSIT PLEELYKRFQ LLEGPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVVEG SFVYKGGKIY KVPSTETEAL ASNLMGMFEK RRFRKFLVFV ANFDENDPKT FEGVDPQTTS MRDVYRKFDL GQDVIDFTGH ALALYRTDDY LDQPCLETVN RIKLYSESLA RYGKSPYLYP LYGLGELPQG FARLSAIYGG TYMLNKPVDD IIMENGKVVG VKSEGEVARC KQLICDPSYI PDRVRKAGQV IRIICILSHP IKNTNDANSC QIIIPQNQVN RKSDIYVCMI SYAHNVAAQG KYIAIASTTV ETTDPEKEVE PALELLEPID QKFVAISDLY EPIDDGCESQ VFCSCSYDAT THFETTCNDI KDIYKRMAGT AFDFENMKRK QNDVFGEAEQ

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Andere Bezeichnung: GDI1 (GDI1 Produkte)

Synonyme: 1A Protein, GDIL Protein, MRX41 Protein, MRX48 Protein, OPHN2 Protein, RABGD1A Protein, RABGDIA Protein, XAP-4 Protein, GDIA Protein, GDIalpha Protein, GDI-1 Protein, zgc:110600 Protein, QccE-14779 Protein, Rab GDI alpha Protein, GDP dissociation inhibitor 1 Protein, GDP dissociation inhibitor 1 S homeolog Protein, guanosine diphosphate (GDP) dissociation inhibitor 1 Protein, GDI1 Protein, gdi1.S Protein, Gdi1 Protein, gdi1 Protein

Hintergrund: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. Recombinant human GDI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 53.0kDa (470aa)

NCBI Accession: NP_001484

UniProt: P31150