PURB Protein (AA 1-312) (His tag)

Produktnummer ABIN5853711

Produktdetails

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-312

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PURB Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMADGDSG SERGGGGGPC GFQPASRGGG EQETQELASK RLDIQNKRFY LDVKQNAKGR FLKIAEVGAG GSKSRLTLSM AVAAEFRDSL GDFIEHYAQL GPSSPEQLAA GAEEGGGPRR ALKSEFLVRE NRKYYLDLKE NQRGRFLRIR QTVNRGGGGF GAGPGPGGLQ SGQTIALPAQ GLIEFRDALA KLIDDYGGED DELAGGPGGG AGGPGGGLYG ELPEGTSITV DSKRFFFDVG CNKYGVFLRV SEVKPSYRNA ITVPFKAWGK FGGAFCRYAD EMKEIQERQR DKLYERRGGG SGGGEESEGE EVDED

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Andere Bezeichnung: PuRB (PURB Produkte)

Synonyme: 2310015K15Rik Protein, AA114818 Protein, Cager-2 Protein, D11Bwg0414e Protein, pur-beta Protein, purb Protein, zgc:65916 Protein, purb-b Protein, purbeta Protein, PURBETA Protein, si:dkey-202n14.1 Protein, purine rich element binding protein B Protein, purine-rich element binding protein Bb Protein, purine-rich element binding protein B L homeolog Protein, purine-rich element binding protein Ba Protein, Purb Protein, purbb Protein, purb.L Protein, PURB Protein, purba Protein

Hintergrund: PuRB is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PuR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Recombinant human PuRB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 35.6kDa (335aa) confirmed by MALDI-TOF

NCBI Accession: NP_150093

UniProt: Q96QR8