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PAICS Protein (AA 1-425) (His tag)
PAICS
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5853635
Produktdetails
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Target
Alle PAICS Proteine anzeigen
PAICS
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-425
Spezies
Alle Spezies für PAICS Proteine
Human
Quelle
Alle Expressionssysteme für PAICS Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses PAICS Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMATAEVL NIGKKLYEGK TKEVYELLDS PGKVLLQSKD QITAGNAARK NHLEGKAAIS NKITSCIFQL LQEAGIKTAF TRKCGETAFI APQCEMIPIE WVCRRIATGS FLKRNPGVKE GYKFYPPKVE LFFKDDANND PQWSEEQLIA AKFCFAGLLI GQTEVDIMSH ATQAIFEILE KSWLPQNCTL VDMKIEFGVD VTTKEIVLAD VIDNDSWRLW PSGDRSQQKD KQSYRDLKEV TPEGLQMVKK NFEWVAERVE LLLKSESQCR VVVLMGSTSD LGHCEKIKKA CGNFGIPCEL RVTSAHKGPD ETLRIKAEYE GDGIPTVFVA VAGRSNGLGP VMSGNTAYPV ISCPPLTPDW GVQDVWSSLR LPSGLGCSTV LSPEGSAQFA AQIFGLSNHL VWSKLRASIL NTWISLKQAD KKIRECNL
Reinheit
> 90 % by SDS - PAGE
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol 0.1M NaCl,1 mM DTT
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
PAICS
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Andere Bezeichnung
PAICS (PAICS Produkte )
Synonyme
cb293 Protein, sb:cb293 Protein, wu:fa28a05 Protein, GB14262 Protein, DDBDRAFT_0218550 Protein, DDBDRAFT_0230088 Protein, DDB_0218550 Protein, DDB_0230088 Protein, AIRC Protein, AS Protein, ADE2 Protein, ADE2H1 Protein, PAIS Protein, Ade2h1 Protein, Airc Protein, ade2 Protein, airc Protein, paics Protein, pais Protein, 2610511I09Rik Protein, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase Protein, multifunctional protein ADE2 Protein, phosphoribosylaminoimidazole carboxylase Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Protein, PAICS Protein, paics Protein, LOC551966 Protein, Tsp_02239a Protein, Tsp_02239 Protein, CNE02500 Protein, purC/E Protein, Paics Protein, paics.2.L Protein
Hintergrund
PAICS, also known as phosphoribosylaminoimidazole carboxylase, is an enzyme involved in nucleotide biosynthesis and in particular in purine biosynthesis. It catalyzes the conversion of 5'-phosphoribosyl-5-aminoimidazole(AIR) into 5'-phosphoribosyl-4-carboxy-5-aminoimidazole (CAIR) as described in the reaction. Recombinant human PAICS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Molekulargewicht
49.5 kDa(448aa) confirmed by MALDI-TOF
NCBI Accession
NP_001072992
UniProt
P22234
Pathways
Chromatin Binding
Zuletzt angesehen
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