TGFBRAP1 Protein (AA 601-860) (His tag)

Produktnummer ABIN5853583

Produktdetails

Target: TGFBRAP1 (Transforming Growth Factor, beta Receptor Associated Protein 1 (TGFBRAP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 601-860

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TGFBRAP1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TGFBRAP1 (Transforming Growth Factor, beta Receptor Associated Protein 1 (TGFBRAP1))

Andere Bezeichnung: TGFBRAP1 (TGFBRAP1 Produkte)

Synonyme: TRAP-1 Protein, TRAP1 Protein, 3110018K12Rik Protein, AU024090 Protein, AU042859 Protein, AW742551 Protein, Trap1 Protein, zgc:162302 Protein, transforming growth factor beta receptor associated protein 1 Protein, transforming growth factor, beta receptor associated protein 1 Protein, TGFBRAP1 Protein, tgfbrap1 Protein, Tgfbrap1 Protein

Hintergrund: TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. It may recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Recombinant human TGFBRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 33 kDa (296aa)

NCBI Accession: NP_004248

UniProt: Q8WUH2