SHFM1 Protein (AA 1-70) (His tag)

Produktnummer ABIN5853387

Produktdetails

Target: SHFM1 (Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-70

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SHFM1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMSEKKQP VDLGLLEEDD EFEEFPAEDW AGLDEDEDAH VWEDNWDDDN VEDDFSNQLR AELEKHGYKM ETS

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.1M NaCl

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SHFM1 (Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1))

Andere Bezeichnung: SHFM1 (SHFM1 Produkte)

Synonyme: DSS1 Protein, ECD Protein, SEM1 Protein, SHFD1 Protein, SHSF1 Protein, Shfdg1 Protein, Shfg Protein, Dss1 Protein, SHFM1 Protein, dss1 Protein, ecd Protein, sem1 Protein, shfd1 Protein, shfdg1 Protein, shfm1 Protein, shfm1.S Protein, shsf1 Protein, wu:fb55c02 Protein, zgc:56203 Protein, zgc:85901 Protein, SEM1, 26S proteasome complex subunit Protein, SEM1, 26S proteasome complex subunit S homeolog Protein, SEM1 Protein, Sem1 Protein, sem1.S Protein, sem1 Protein

Hintergrund: SHFM1, as known as 26S proteasome complex subunit DSS1, has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. Recombinant human SHFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Molekulargewicht: 10.7kDa (93aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_006295

UniProt: P60896