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TRIAP1 Protein (AA 1-76) (His tag)
TRIAP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5853375
Produktdetails
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Target
Alle TRIAP1 Proteine anzeigen
TRIAP1
(TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-76
Spezies
Alle Spezies für TRIAP1 Proteine
Human
Quelle
Alle Expressionssysteme für TRIAP1 Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses TRIAP1 Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS
Reinheit
> 90 % by SDS - PAGE
Top Product
Discover our top product TRIAP1 Protein
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 20 % glycerol, 1 mM DTT
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
TRIAP1
(TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
Andere Bezeichnung
TRIAP1 (TRIAP1 Produkte )
Synonyme
MDM35 Protein, P53CSV Protein, WF-1 Protein, 1810015M01Rik Protein, AU020874 Protein, AU043831 Protein, P53csv Protein, Wf-1 Protein, p53csv-A Protein, triap1 Protein, triap1a Protein, p53csv-B Protein, triap1-a Protein, triap1-b Protein, triap1b Protein, zgc:112025 Protein, TP53 regulated inhibitor of apoptosis 1 Protein, TP53 regulated inhibitor of apoptosis 1 S homeolog Protein, TP53 regulated inhibitor of apoptosis 1 L homeolog Protein, TRIAP1 Protein, Triap1 Protein, triap1.S Protein, triap1.L Protein, triap1 Protein
Hintergrund
TP53-regulated inhibitor of apoptosis 1, also known as TRIAP1, contains a p53-binding site within its second exon and the reduction of expression by small interfering RNA enhanced apoptosis, whereas overexpression protected cells from apoptosis caused by DNA damage. TRIAP1 is induced significantly when cells have a low level of genotoxic stresses, but not when DNA damage is severe. TRIAP1 can modulate apoptotic pathways through interaction with Hsp70 that probably inhibits activity of apoptosis protease activating factor-1. Recombinant human TRIAP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molekulargewicht
11.2kDa (99aa), confirmed by MALDI-TOF
NCBI Accession
NP_057483
UniProt
O43715
Pathways
Negative Regulation of intrinsic apoptotic Signaling
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