Crystallography grade
Acad8
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS, Crys
zgc:55874 Protein, DDBDRAFT_0219367 Protein, DDBDRAFT_0237710 Protein, DDB_0219367 Protein, DDB_0237710 Protein, ACAD-8 Protein, ARC42 Protein, RGD1564209 Protein, 2310016C19Rik Protein, AI786953 Protein, acyl-CoA dehydrogenase family member 8 L homeolog Protein, acyl-CoA dehydrogenase family, member 8 Protein, acyl-CoA dehydrogenase family member 8 Protein, acyl-CoA dehydrogenase Protein, acyl-Coenzyme A dehydrogenase family, member 8 Protein, acad8.L Protein, acad8 Protein, ACAD8 Protein, LOC100231097 Protein, Acad8 Protein
Hintergrund
ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency. Recombinant human ACAD8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.