FHL3 Protein (AA 1-280) (His tag)

Produktnummer ABIN5853348

Produktdetails

Target: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-280

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FHL3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMSESFDC AKCNESLYGR KYIQTDSGPY CVPCYDNTFA NTCAECQQLI GHDSRELFYE DRHFHEGCFR CCRCQRSLAD EPFTCQDSEL LCNDCYCSAF SSQCSACGET VMPGSRKLEY GGQTWHEHCF LCSGCEQPLG SRSFVPDKGA HYCVPCYENK FAPRCARCSK TLTQGGVTYR DQPWHRECLV CTGCQTPLAG QQFTSRDEDP YCVACFGELF APKCSSCKRP IVGLGGGKYV SFEDRHWHHN CFSCARCSTS LVGQGFVPDG DQVLCQGCSQ AGP

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Andere Bezeichnung: FHL3 (FHL3 Produkte)

Synonyme: slim2 Protein, MGC79794 Protein, fb09g09 Protein, wu:fb09g09 Protein, zgc:63514 Protein, fd57e01 Protein, fhl3 Protein, wu:fd57e01 Protein, SLIM2 Protein, four and a half LIM domains 3 Protein, four and a half LIM domains 3 S homeolog Protein, four and a half LIM domains 3b Protein, four and a half LIM domains 3a Protein, FHL3 Protein, fhl3.S Protein, fhl3 Protein, fhl3b Protein, fhl3a Protein, Fhl3 Protein

Hintergrund: FHL3 is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human FHL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 33.6 kDa (303aa) confirmed by MALDI-TOF

NCBI Accession: NP_004459

UniProt: Q13643